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Inhibition of SP1 by the mithramycin analog EC-8042 efficiently targets tumor initiating cells in sarcoma

Tumor initiating cells (TICs), responsible for tumor initiation, and cancer stem cells (CSCs), responsible for tumor expansion and propagation, are often resistant to chemotherapeutic agents. To find therapeutic targets against sarcoma initiating and propagating cells we used models of myxoid liposa...

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Detalles Bibliográficos
Autores principales: Tornin, Juan, Martinez-Cruzado, Lucia, Santos, Laura, Rodriguez, Aida, Núñez, Luz-Elena, Oro, Patricia, Hermosilla, Maria Ana, Allonca, Eva, Fernández-García, Maria Teresa, Astudillo, Aurora, Suarez, Carlos, Morís, Francisco, Rodriguez, Rene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058729/
https://www.ncbi.nlm.nih.gov/pubmed/27105533
http://dx.doi.org/10.18632/oncotarget.8817