Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation

Small cell lung cancer (SCLC) is the most aggressive type of lung cancer with high mortality. One of the MYC family genes, MYC, MYCL or MYCN, is amplified in ~20% of the SCLCs; therefore, MYC proteins are potential therapeutic targets in SCLC patients. We investigated the therapeutic impact of Omomy...

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Detalles Bibliográficos
Autores principales: Fiorentino, Francesco Paolo, Tokgün, Elvan, Solé-Sánchez, Sònia, Giampaolo, Sabrina, Tokgün, Onur, Jauset, Toni, Kohno, Takashi, Perucho, Manuel, Soucek, Laura, Yokota, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058735/
https://www.ncbi.nlm.nih.gov/pubmed/27105536
http://dx.doi.org/10.18632/oncotarget.8826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058735/
https://www.ncbi.nlm.nih.gov/pubmed/27105536
http://dx.doi.org/10.18632/oncotarget.8826

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