Cargando…
Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation
Small cell lung cancer (SCLC) is the most aggressive type of lung cancer with high mortality. One of the MYC family genes, MYC, MYCL or MYCN, is amplified in ~20% of the SCLCs; therefore, MYC proteins are potential therapeutic targets in SCLC patients. We investigated the therapeutic impact of Omomy...
Autores principales: | Fiorentino, Francesco Paolo, Tokgün, Elvan, Solé-Sánchez, Sònia, Giampaolo, Sabrina, Tokgün, Onur, Jauset, Toni, Kohno, Takashi, Perucho, Manuel, Soucek, Laura, Yokota, Jun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058735/ https://www.ncbi.nlm.nih.gov/pubmed/27105536 http://dx.doi.org/10.18632/oncotarget.8826 |
Ejemplares similares
-
Treatment of STING-associated vasculopathy with onset in infancy in patients carrying a novel mutation in the TMEM173 gene with the JAK3-inhibitor tofacitinib
por: Tokgun, Pervin Elvan, et al.
Publicado: (2023) -
Therapeutic Effect of Teneligliptin in Drug-Induced Nephrotoxicity: An In-Vitro Study
por: Becerir, Tülay, et al.
Publicado: (2022) -
Protective effect of insulin and glucose at different concentrations on penicillin-induced astrocyte death on the primer astroglial cell line☆
por: Özdemir, Mehmet Bülent, et al.
Publicado: (2012) -
Two Novel CEBPA Mutations in a Turkish Patient with Acute Myeloid Leukemia
por: Tokgun, PE, et al.
Publicado: (2021) -
NGS Analysis Confirms Common TP53 and RB1 Mutations, and Suggests MYC Amplification in Ocular Adnexal Sebaceous Carcinomas
por: Peterson, Cornelia, et al.
Publicado: (2021)