Nuclear receptor 4A1 (NR4A1) as a drug target for treating rhabdomyosarcoma (RMS)

The orphan nuclear receptor NR4A1 is expressed in tumors from rhabdomyosarcoma (RMS) patients and Rh30 and RD RMS cell lines, and we used RNA interference (RNAi) to investigate the role of this receptor in RMS cells. Knockdown of NR4A1 in Rh30 cells decreased cell proliferation, induced Annexin V st...

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Detalles Bibliográficos
Autores principales: Lacey, Alexandra, Hedrick, Erik, Li, Xi, Patel, Ketan, Doddapaneni, Ravi, Singh, Mandip, Safe, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058754/
https://www.ncbi.nlm.nih.gov/pubmed/27144436
http://dx.doi.org/10.18632/oncotarget.9112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058754/
https://www.ncbi.nlm.nih.gov/pubmed/27144436
http://dx.doi.org/10.18632/oncotarget.9112

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