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IDH-1(R132H) mutation status in diffuse glioma patients: implications for classification

WHO(2007) grading of diffuse gliomas in adults is well-established. However, IDH mutations make classification of gliomas according to the WHO(2007) edition controversial. Here, we characterized IDH-1(R132H mut) status in a cohort of 670 adult patients with different WHO(2007) grades of diffuse glio...

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Detalles Bibliográficos
Autores principales: Wang, Peng-fei, Liu, Ning, Song, Hong-wang, Yao, Kun, Jiang, Tao, Li, Shou-wei, Yan, Chang-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058765/
https://www.ncbi.nlm.nih.gov/pubmed/27120786
http://dx.doi.org/10.18632/oncotarget.8918