NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner

The GDNF (Glial cell line-derived neurotrophic factor)/Ret/Akt signaling pathway is essential to the development of ENS (enteric nervous system) as well as kidney. We previously showed that the HECT-type E3 ligase NEDL2 (Nedd4-like ligase 2) is required for the ENS development by activating GDNF/Ret...

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Detalles Bibliográficos
Autores principales: Qiu, Xiao, Wei, Rongfei, Li, Yang, Zhu, Qiong, Xiong, Cong, Chen, Yuhan, Zhang, Yuan, Lu, Kefeng, He, Fuchu, Zhang, Lingqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058769/
https://www.ncbi.nlm.nih.gov/pubmed/27119228
http://dx.doi.org/10.18632/oncotarget.8951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058769/
https://www.ncbi.nlm.nih.gov/pubmed/27119228
http://dx.doi.org/10.18632/oncotarget.8951

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