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CTNNA1 hypermethylation, a frequent event in acute myeloid leukemia, is independently associated with an adverse outcome

The aim of this study is to evaluate the frequency of CTNNA1 hypermethylation in acute myeloid leukemia (AML) patients in an attempt to improve molecular prognostic model. CTNNA1 promoter methylation levels in 319 newly diagnosed AML patients were detected using quantitative methylation-specific pol...

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Detalles Bibliográficos
Autores principales: Li, Mianyang, Gao, Li, Li, Zhenling, Sun, Junzhong, Zhang, Hui, Duan, Haoqing, Ma, Yigai, Wang, Chengbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058770/
https://www.ncbi.nlm.nih.gov/pubmed/27129146
http://dx.doi.org/10.18632/oncotarget.8962