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Narrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypes

Functional genomics approaches such as gain- and loss-of-function screening can efficiently reveal genes that control cancer cell growth, survival, signal transduction, and drug resistance, but distilling the results of large-scale screens into actionable therapeutic strategies is challenging given...

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Detalles Bibliográficos
Autores principales: Singleton, Katherine R., Wood, Kris C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059112/
https://www.ncbi.nlm.nih.gov/pubmed/27738492
http://dx.doi.org/10.18632/genesandcancer.112