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Narrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypes
Functional genomics approaches such as gain- and loss-of-function screening can efficiently reveal genes that control cancer cell growth, survival, signal transduction, and drug resistance, but distilling the results of large-scale screens into actionable therapeutic strategies is challenging given...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059112/ https://www.ncbi.nlm.nih.gov/pubmed/27738492 http://dx.doi.org/10.18632/genesandcancer.112 |