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Akabane virus nonstructural protein NSm regulates viral growth and pathogenicity in a mouse model

The biological function of a nonstructural protein, NSm, of Akabane virus (AKAV) is unknown. In this study, we generated a series of NSm deletion mutant viruses by reverse genetics and compared their phenotypes. The mutant in which the NSm coding region was almost completely deleted could not be res...

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Detalles Bibliográficos
Autores principales: ISHIHARA, Yukari, SHIODA, Chieko, BANGPHOOMI, Norasuthi, SUGIURA, Keita, SAEKI, Kohei, TSUDA, Shumpei, IWANAGA, Tatsuya, TAKENAKA-UEMA, Akiko, KATO, Kentaro, MURAKAMI, Shin, UCHIDA, Kazuyuki, AKASHI, Hiroomi, HORIMOTO, Taisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059365/
https://www.ncbi.nlm.nih.gov/pubmed/27181086
http://dx.doi.org/10.1292/jvms.16-0140