Functions of the Alzheimer’s Disease Protease BACE1 at the Synapse in the Central Nervous System

Inhibition of the protease β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) is a promising treatment strategy for Alzheimer’s disease, and a number of BACE inhibitors are currently progressing through clinical trials. The strategy aims to decrease production of amyloid-β (Aβ) peptide from...

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Detalles Bibliográficos
Autores principales: Munro, Kathryn M., Nash, Amelia, Pigoni, Martina, Lichtenthaler, Stefan F., Gunnersen, Jenny M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059407/
https://www.ncbi.nlm.nih.gov/pubmed/27456313
http://dx.doi.org/10.1007/s12031-016-0800-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059407/
https://www.ncbi.nlm.nih.gov/pubmed/27456313
http://dx.doi.org/10.1007/s12031-016-0800-1

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