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Functions of the Alzheimer’s Disease Protease BACE1 at the Synapse in the Central Nervous System
Inhibition of the protease β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) is a promising treatment strategy for Alzheimer’s disease, and a number of BACE inhibitors are currently progressing through clinical trials. The strategy aims to decrease production of amyloid-β (Aβ) peptide from...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059407/ https://www.ncbi.nlm.nih.gov/pubmed/27456313 http://dx.doi.org/10.1007/s12031-016-0800-1 |