Cargando…
Excess of mutational jackpot events in expanding populations revealed by spatial Luria–Delbrück experiments
The genetic diversity of growing cellular populations, such as biofilms, solid tumours or developing embryos, is thought to be dominated by rare, exceptionally large mutant clones. Yet, the emergence of these mutational jackpot events is only understood in well-mixed populations, where they stem fro...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059437/ https://www.ncbi.nlm.nih.gov/pubmed/27694797 http://dx.doi.org/10.1038/ncomms12760 |