Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NFκB Pathway Suppression

Advanced glycation end products (AGEs) are major inflammatory mediators in diabetes, affecting atherosclerosis progression via macrophages. Metformin slows diabetic atherosclerosis progression through mechanisms that remain to be fully elucidated. The present study of murine bone marrow derived macr...

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Detalles Bibliográficos
Autores principales: Zhou, Zhong'e, Tang, Yong, Jin, Xian, Chen, Chengjun, Lu, Yi, Liu, Liang, Shen, Chengxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059570/
https://www.ncbi.nlm.nih.gov/pubmed/27761470
http://dx.doi.org/10.1155/2016/4847812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059570/
https://www.ncbi.nlm.nih.gov/pubmed/27761470
http://dx.doi.org/10.1155/2016/4847812

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