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Epithelial cell-derived microvesicles activate macrophages and promote inflammation via microvesicle-containing microRNAs

Intercellular communications between lung epithelial cells and alveolar macrophages play an essential role in host defense against acute lung injury. Hyperoxia-induced oxidative stress is an established model to mimic human lung injury. We show that after hyperoxia-associated oxidative stress, a lar...

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Detalles Bibliográficos
Autores principales: Lee, Heedoo, Zhang, Duo, Zhu, Ziwen, Dela Cruz, Charles S., Jin, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059671/
https://www.ncbi.nlm.nih.gov/pubmed/27731391
http://dx.doi.org/10.1038/srep35250