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Hydroxysafflor yellow A alleviates myocardial ischemia/reperfusion in hyperlipidemic animals through the suppression of TLR4 signaling

Hyperlipidemia aggravates myocardial ischemia/reperfusion (MI/R) injury through stimulating excessive inflammatory response. Therefore, blockade of inflammatory signal is a potential therapeutic management for MI/R complicated with hyperlipidemia. Hydroxysafflor yellow A (HSYA, a monomer extracted f...

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Detalles Bibliográficos
Autores principales: Han, Dan, Wei, Jie, Zhang, Rui, Ma, Wenhuan, Shen, Chen, Feng, Yidong, Xia, Nian, Xu, Dan, Cai, Dongcheng, Li, Yunman, Fang, Weirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059673/
https://www.ncbi.nlm.nih.gov/pubmed/27731393
http://dx.doi.org/10.1038/srep35319