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Purine and pyrimidine metabolism: Convergent evidence on chronic antidepressant treatment response in mice and humans

Selective Serotonin Reuptake Inhibitors (SSRIs) are commonly used drugs for the treatment of psychiatric diseases including major depressive disorder (MDD). For unknown reasons a substantial number of patients do not show any improvement during or after SSRI treatment. We treated DBA/2J mice for 28...

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Detalles Bibliográficos
Autores principales: Park, Dong Ik, Dournes, Carine, Sillaber, Inge, Uhr, Manfred, Asara, John M., Gassen, Nils C., Rein, Theo, Ising, Marcus, Webhofer, Christian, Filiou, Michaela D., Müller, Marianne B., Turck, Christoph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059694/
https://www.ncbi.nlm.nih.gov/pubmed/27731396
http://dx.doi.org/10.1038/srep35317