FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription

FUS (Fused-in-Sarcoma) is a multifunctional DNA/RNA binding protein linked to familial amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD). Since FUS is localized mainly in the nucleus with nucleo-cytoplasmic shuttling, it is critical to understand physiological functions in the nucleus...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Atsushi, Takanashi, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059712/
https://www.ncbi.nlm.nih.gov/pubmed/27731383
http://dx.doi.org/10.1038/srep35195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059712/
https://www.ncbi.nlm.nih.gov/pubmed/27731383
http://dx.doi.org/10.1038/srep35195

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