Cargando…

Regulation of actin catch-slip bonds with a RhoA-formin module

The dynamic turnover of the actin cytoskeleton is regulated cooperatively by force and biochemical signaling. We previously demonstrated that actin depolymerization under force is governed by catch-slip bonds mediated by force-induced K113:E195 salt-bridges. Yet, the biochemical regulation as well a...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Cho-yin, Lou, Jizhong, Wen, Kuo-Kuang, McKane, Melissa, Eskin, Suzanne G., Rubenstein, Peter A., Chien, Shu, Ono, Shoichiro, Zhu, Cheng, McIntire, Larry V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059732/
https://www.ncbi.nlm.nih.gov/pubmed/27731359
http://dx.doi.org/10.1038/srep35058