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Regulation of actin catch-slip bonds with a RhoA-formin module
The dynamic turnover of the actin cytoskeleton is regulated cooperatively by force and biochemical signaling. We previously demonstrated that actin depolymerization under force is governed by catch-slip bonds mediated by force-induced K113:E195 salt-bridges. Yet, the biochemical regulation as well a...
Autores principales: | Lee, Cho-yin, Lou, Jizhong, Wen, Kuo-Kuang, McKane, Melissa, Eskin, Suzanne G., Rubenstein, Peter A., Chien, Shu, Ono, Shoichiro, Zhu, Cheng, McIntire, Larry V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059732/ https://www.ncbi.nlm.nih.gov/pubmed/27731359 http://dx.doi.org/10.1038/srep35058 |
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