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Protein-dependent Membrane Interaction of A Partially Disordered Protein Complex with Oleic Acid: Implications for Cancer Lipidomics

Bovine α-lactalbumin (BLA) forms cytotoxic complexes with oleic acid (OA) that perturbs tumor cell membranes, but molecular determinants of these membrane-interactions remain poorly understood. Here, we aim to obtain molecular insights into the interaction of BLA/BLA-OA complex with model membranes....

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Detalles Bibliográficos
Autores principales: Chaudhuri, Arunima, Prasanna, Xavier, Agiru, Priyanka, Chakraborty, Hirak, Rydström, Anna, Ho, James C. S., Svanborg, Catharina, Sengupta, Durba, Chattopadhyay, Amitabha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059734/
https://www.ncbi.nlm.nih.gov/pubmed/27731329
http://dx.doi.org/10.1038/srep35015