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A distinct holoenzyme organization for two-subunit pyruvate carboxylase

Pyruvate carboxylase (PC) has important roles in metabolism and is crucial for virulence for some pathogenic bacteria. PC contains biotin carboxylase (BC), carboxyltransferase (CT) and biotin carboxyl carrier protein (BCCP) components. It is a single-chain enzyme in eukaryotes and most bacteria, and...

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Detalles Bibliográficos
Autores principales: Choi, Philip H., Jo, Jeanyoung, Lin, Yu-Cheng, Lin, Min-Han, Chou, Chi-Yuan, Dietrich, Lars E. P., Tong, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059739/
https://www.ncbi.nlm.nih.gov/pubmed/27708276
http://dx.doi.org/10.1038/ncomms12713