Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing

The TOR and Insulin/IGF signalling (IIS) network controls growth, metabolism and ageing. Although reducing TOR or insulin signalling can be beneficial for ageing, it can be detrimental for wound healing, but the reasons for this difference are unknown. Here we show that IIS is activated in the cells...

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Detalles Bibliográficos
Autores principales: Kakanj, Parisa, Moussian, Bernard, Grönke, Sebastian, Bustos, Victor, Eming, Sabine A., Partridge, Linda, Leptin, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059774/
https://www.ncbi.nlm.nih.gov/pubmed/27713427
http://dx.doi.org/10.1038/ncomms12972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059774/
https://www.ncbi.nlm.nih.gov/pubmed/27713427
http://dx.doi.org/10.1038/ncomms12972

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