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Endoglin integrates BMP and Wnt signalling to induce haematopoiesis through JDP2

Mechanisms of haematopoietic and cardiac patterning remain poorly understood. Here we show that the BMP and Wnt signalling pathways are integrated in an endoglin (Eng)-dependent manner in cardiac and haematopoietic lineage specification. Eng is expressed in early mesoderm and marks both haematopoiet...

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Detalles Bibliográficos
Autores principales: Baik, June, Magli, Alessandro, Tahara, Naoyuki, Swanson, Scott A., Koyano-Nakagawa, Naoko, Borges, Luciene, Stewart, Ron, Garry, Daniel J., Kawakami, Yasuhiko, Thomson, James A., Perlingeiro, Rita C. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059784/
https://www.ncbi.nlm.nih.gov/pubmed/27713415
http://dx.doi.org/10.1038/ncomms13101