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HSV-1-induced activation of NF-κB protects U937 monocytic cells against both virus replication and apoptosis

The transcription factor nuclear factor-kappa B (NF-κB) is a crucial player of the antiviral innate response. Intriguingly, however, NF-κB activation is assumed to favour herpes simplex virus (HSV) infection rather than restrict it. Apoptosis, a form of innate response to viruses, is completely inhi...

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Detalles Bibliográficos
Autores principales: Marino-Merlo, Francesca, Papaianni, Emanuela, Medici, Maria Antonietta, Macchi, Beatrice, Grelli, Sandro, Mosca, Claudia, Borner, Christoph, Mastino, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059854/
https://www.ncbi.nlm.nih.gov/pubmed/27584793
http://dx.doi.org/10.1038/cddis.2016.250