Nitric oxide released from JS-K induces cell death by mitotic catastrophe as part of necrosis in glioblastoma multiforme

The nitric oxide (NO) donor JS-K is specifically activated by glutathione S-transferases (GSTs) in GST-overexpressing cells. We have shown the induction of cell death in glioblastoma multiforme (GBM) cells at high JS-K doses but the mechanism remains unclear. The aim of this study was to determine w...

Descripción completa

Detalles Bibliográficos
Autores principales: Günzle, Jessica, Osterberg, Nadja, Saavedra, Joseph E, Weyerbrock, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059858/
https://www.ncbi.nlm.nih.gov/pubmed/27584787
http://dx.doi.org/10.1038/cddis.2016.254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059858/
https://www.ncbi.nlm.nih.gov/pubmed/27584787
http://dx.doi.org/10.1038/cddis.2016.254

Ejemplares similares