Pharmacologic inhibition of reactive gliosis blocks TNF-α-mediated neuronal apoptosis

Reactive gliosis is an early pathological feature common to most neurodegenerative diseases, yet its regulation and impact remain poorly understood. Normally astrocytes maintain a critical homeostatic balance. After stress or injury they undergo rapid parainflammatory activation, characterized by hy...

Descripción completa

Detalles Bibliográficos
Autores principales: Livne-Bar, Izhar, Lam, Susy, Chan, Darren, Guo, Xiaoxin, Askar, Idil, Nahirnyj, Adrian, Flanagan, John G, Sivak, Jeremy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059876/
https://www.ncbi.nlm.nih.gov/pubmed/27685630
http://dx.doi.org/10.1038/cddis.2016.277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059876/
https://www.ncbi.nlm.nih.gov/pubmed/27685630
http://dx.doi.org/10.1038/cddis.2016.277

Ejemplares similares