Cargando…

Pharmacologic inhibition of reactive gliosis blocks TNF-α-mediated neuronal apoptosis

Reactive gliosis is an early pathological feature common to most neurodegenerative diseases, yet its regulation and impact remain poorly understood. Normally astrocytes maintain a critical homeostatic balance. After stress or injury they undergo rapid parainflammatory activation, characterized by hy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Livne-Bar, Izhar, Lam, Susy, Chan, Darren, Guo, Xiaoxin, Askar, Idil, Nahirnyj, Adrian, Flanagan, John G, Sivak, Jeremy M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059876/ https://www.ncbi.nlm.nih.gov/pubmed/27685630 http://dx.doi.org/10.1038/cddis.2016.277

Ejemplares similares

ROS Detoxification and Proinflammatory Cytokines Are Linked by p38 MAPK Signaling in a Model of Mature Astrocyte Activation
por: Nahirnyj, Adrian, et al.
Publicado: (2013)

An inducible rodent glaucoma model that exhibits gradual sustained increase in intraocular pressure with distinct inner retina and optic nerve inflammation
por: Mathew, David J., et al.
Publicado: (2021)

4395 alpha-Synuclein Induced Reactive Gliosis
por: Carey, Sean David, et al.
Publicado: (2020)

Minocycline reduces reactive gliosis in the rat model of hydrocephalus
por: Xu, Hao, et al.
Publicado: (2012)

Stroke subtype-dependent synapse elimination by reactive gliosis in mice
por: Shi, Xiaojing, et al.
Publicado: (2021)

Meteorin is upregulated in reactive astrocytes and functions as a negative feedback effector in reactive gliosis
por: LEE, HYE SHIN, et al.
Publicado: (2015)

Therapeutic Strategies Against Apoptosis and Gliosis
por: Ko, Il-Gyu
Publicado: (2020)

Proliferative reactive gliosis is compatible with glial metabolic support and neuronal function
por: Vázquez-Chona, Félix R, et al.
Publicado: (2011)

Sirtuin modulators control reactive gliosis in an in vitro model of Alzheimer’s disease
por: Scuderi, Caterina, et al.
Publicado: (2014)

The Time Course of Gene Expression during Reactive Gliosis in the Optic Nerve
por: Qu, Juan, et al.
Publicado: (2013)

Retinal cell death dependent reactive proliferative gliosis in the mouse retina
por: Sardar Pasha, Sheik Pran Babu, et al.
Publicado: (2017)

Microglia activation is essential for BMP7-mediated retinal reactive gliosis
por: Dharmarajan, Subramanian, et al.
Publicado: (2017)

An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14
por: Alqawlaq, Samih, et al.
Publicado: (2020)

Inhibition of Reactive Gliosis Attenuates Excitotoxicity-Mediated Death of Retinal Ganglion Cells
por: Ganesh, Bhagyalaxmi S., et al.
Publicado: (2011)

The involvement of mast cells in the irinotecan-induced enteric neurons loss and reactive gliosis
por: Nogueira, Ludmila T., et al.
Publicado: (2017)

Author Correction: Stroke subtype-dependent synapse elimination by reactive gliosis in mice
por: Shi, Xiaojing, et al.
Publicado: (2022)

Agomir-331 Suppresses Reactive Gliosis and Neuroinflammation after Traumatic Brain Injury
por: Wang, Jin-Xing, et al.
Publicado: (2023)

Immature Teratoma With Metastatic Gliosis
por: Ahoussougbemey Mele, Ange, et al.
Publicado: (2022)

Inhibition of Reactive Gliosis Prevents Neovascular Growth in the Mouse Model of Oxygen-Induced Retinopathy
por: DeNiro, Michael, et al.
Publicado: (2011)

Gabapentin Administration Reduces Reactive Gliosis and Neurodegeneration after Pilocarpine-Induced Status Epilepticus
por: Rossi, Alicia Raquel, et al.
Publicado: (2013)

Bone morphogenetic protein 7 regulates reactive gliosis in retinal astrocytes and Müller glia
por: Dharmarajan, Subramanian, et al.
Publicado: (2014)

Recombinant Integrin β1 Signal Peptide Blocks Gliosis Induced by Aβ Oligomers
por: Ortiz-Sanz, Carolina, et al.
Publicado: (2022)

A versatile 3D culture model facilitates monitoring of astrocytes undergoing reactive gliosis
por: East, Emma, et al.
Publicado: (2009)

Palmitoylethanolamide controls reactive gliosis and exerts neuroprotective functions in a rat model of Alzheimer's disease
por: Scuderi, C, et al.
Publicado: (2014)

Retraction: Inhibition of reactive gliosis prevents neovascular growth in the mouse model of oxygen-induced retinopathy
Publicado: (2019)

Dysregulated brain regulatory T cells fail to control reactive gliosis following repeated antigen stimulation
por: Prasad, Sujata, et al.
Publicado: (2023)

β-adrenergic signaling triggers enteric glial reactivity and acute enteric gliosis during surgery
por: Leven, Patrick, et al.
Publicado: (2023)

Reactive gliosis and neuroinflammation: prime suspects in the pathophysiology of post-acute neuroCOVID-19 syndrome
por: Saucier, Jacob, et al.
Publicado: (2023)

Pharmacological Administration of the Isoflavone Daidzein Enhances Cell Proliferation and Reduces High Fat Diet-Induced Apoptosis and Gliosis in the Rat Hippocampus
por: Rivera, Patricia, et al.
Publicado: (2013)

Attenuation of Reactive Gliosis Does Not Affect Infarct Volume in Neonatal Hypoxic-Ischemic Brain Injury in Mice
por: Järlestedt, Katarina, et al.
Publicado: (2010)

Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation
por: Tassoni, Alessia, et al.
Publicado: (2015)

Differential Cannabinoid Receptor Expression during Reactive Gliosis: a Possible Implication for a Nonpsychotropic Neuroprotection
por: De Filippis, Daniele, et al.
Publicado: (2009)

Reactive gliosis mimicking tumor recurrence – a case series documenting MRI abnormalities and neuropathological correlates
por: Kearney, Hugh, et al.
Publicado: (2018)

The Lentiviral Vector Pseudotyped by Modified Rabies Glycoprotein Does Not Cause Reactive Gliosis and Neurodegeneration in Rat Hippocampus
por: Farzaneh, Mostafa, et al.
Publicado: (2019)

Changes in Brain Matrix Glycan Sulfation Associate With Reactive Gliosis and Motor Coordination in Mice With Head Trauma
por: Alonge, Kimberly M., et al.
Publicado: (2021)

Metabolic Enzyme Alterations and Astrocyte Dysfunction in a Murine Model of Alexander Disease With Severe Reactive Gliosis
por: Heaven, Michael R., et al.
Publicado: (2021)

An Intracranial Gliosis Mimicking Neoplasm: A Dilemma
por: Shao, Zhi-hong, et al.
Publicado: (2016)

NODULAR EPIRETINAL MÜLLER CELL GLIOSIS IN THE FOVEA
por: Jung, Jesse J., et al.
Publicado: (2023)

Emerging Roles of Astrocytes in Neuro-Vascular Unit and the Tripartite Synapse With Emphasis on Reactive Gliosis in the Context of Alzheimer’s Disease
por: Liu, Cai-Yun, et al.
Publicado: (2018)

Recall Responses from Brain-Resident Memory CD8(+) T Cells (bT(RM)) Induce Reactive Gliosis
por: Prasad, Sujata, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_bm8i2poeb2q5dc1dlcrc5ql2ub