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Activation of necroptosis in human and experimental cholestasis

Cholestasis encompasses liver injury and inflammation. Necroptosis, a necrotic cell death pathway regulated by receptor-interacting protein (RIP) 3, may mediate cell death and inflammation in the liver. We aimed to investigate the role of necroptosis in mediating deleterious processes associated wit...

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Detalles Bibliográficos
Autores principales: Afonso, Marta B, Rodrigues, Pedro M, Simão, André L, Ofengeim, Dimitry, Carvalho, Tânia, Amaral, Joana D, Gaspar, Maria M, Cortez-Pinto, Helena, Castro, Rui E, Yuan, Junying, Rodrigues, Cecília M P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059878/
https://www.ncbi.nlm.nih.gov/pubmed/27685634
http://dx.doi.org/10.1038/cddis.2016.280