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Activation of necroptosis in human and experimental cholestasis
Cholestasis encompasses liver injury and inflammation. Necroptosis, a necrotic cell death pathway regulated by receptor-interacting protein (RIP) 3, may mediate cell death and inflammation in the liver. We aimed to investigate the role of necroptosis in mediating deleterious processes associated wit...
Autores principales: | Afonso, Marta B, Rodrigues, Pedro M, Simão, André L, Ofengeim, Dimitry, Carvalho, Tânia, Amaral, Joana D, Gaspar, Maria M, Cortez-Pinto, Helena, Castro, Rui E, Yuan, Junying, Rodrigues, Cecília M P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059878/ https://www.ncbi.nlm.nih.gov/pubmed/27685634 http://dx.doi.org/10.1038/cddis.2016.280 |
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