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miR-612 suppresses stem cell-like property of hepatocellular carcinoma cells by modulating Sp1/Nanog signaling

In our previous study we found that miR-612 negatively regulated stem cell-like property and tumor metastasis of hepatocellular carcinoma cells (HCC). In this study, we try to elucidate underlying mechanism of the regulation, and find that miR-612 inversely modulate the mRNA and protein level of epi...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Liu, Dong-Li, Dong, Li-Li, Wen, Duo, Shi, Dong-Min, Zhou, Jian, Fan, Jia, Wu, Wei-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059880/
https://www.ncbi.nlm.nih.gov/pubmed/27685621
http://dx.doi.org/10.1038/cddis.2016.282