CHK1 and RAD51 activation after DNA damage is regulated via urokinase receptor/TLR4 signaling

Mechanisms of DNA damage and repair signaling are not completely understood that hinder the efficiency of cancer therapy. Urokinase-type plasminogen activator receptor (PLAUR) is highly expressed in most solid cancers and serves as a marker of poor prognosis. We show that PLAUR actively promotes DNA...

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Detalles Bibliográficos
Autores principales: Narayanaswamy, Pavan B, Tkachuk, Sergey, Haller, Hermann, Dumler, Inna, Kiyan, Yulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059885/
https://www.ncbi.nlm.nih.gov/pubmed/27685627
http://dx.doi.org/10.1038/cddis.2016.291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059885/
https://www.ncbi.nlm.nih.gov/pubmed/27685627
http://dx.doi.org/10.1038/cddis.2016.291

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