TAK1 regulates caspase 8 activation and necroptotic signaling via multiple cell death checkpoints

Necroptosis has emerged as a new form of programmed cell death implicated in a number of pathological conditions such as ischemic injury, neurodegenerative disease, and viral infection. Recent studies indicate that TGFβ-activated kinase 1 (TAK1) is nodal regulator of necroptotic cell death, although...

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Detalles Bibliográficos
Autores principales: Guo, Xiaoyun, Yin, Haifeng, Chen, Yi, Li, Lei, Li, Jing, Liu, Qinghang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059887/
https://www.ncbi.nlm.nih.gov/pubmed/27685625
http://dx.doi.org/10.1038/cddis.2016.294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059887/
https://www.ncbi.nlm.nih.gov/pubmed/27685625
http://dx.doi.org/10.1038/cddis.2016.294

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