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Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure
Acute liver failure (ALF) is a life-threatening systemic disorder. Here we investigated the impact of circulating histones, recently identified inflammatory mediators, on systemic inflammation and liver injury in murine models and patients with ALF. We analyzed histone levels in blood samples from 6...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059889/ https://www.ncbi.nlm.nih.gov/pubmed/27685635 http://dx.doi.org/10.1038/cddis.2016.303 |