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Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure

Acute liver failure (ALF) is a life-threatening systemic disorder. Here we investigated the impact of circulating histones, recently identified inflammatory mediators, on systemic inflammation and liver injury in murine models and patients with ALF. We analyzed histone levels in blood samples from 6...

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Detalles Bibliográficos
Autores principales:	Wen, Zongmei, Lei, Zhen, Yao, Lu, Jiang, Ping, Gu, Tao, Ren, Feng, Liu, Yan, Gou, Chunyan, Li, Xiuhui, Wen, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059889/ https://www.ncbi.nlm.nih.gov/pubmed/27685635 http://dx.doi.org/10.1038/cddis.2016.303

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