Kinase-independent function of RIP1, critical for mature T-cell survival and proliferation

The death receptor, Fas, triggers apoptotic death and is essential for maintaining homeostasis in the peripheral lymphoid organs. RIP1 was originally cloned when searching for Fas-binding proteins and was later shown to associate also with the signaling complex of TNFR1. Although Fas exclusively ind...

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Detalles Bibliográficos
Autores principales: Dowling, John P, Cai, Yubo, Bertin, John, Gough, Peter J, Zhang, Jianke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059890/
https://www.ncbi.nlm.nih.gov/pubmed/27685623
http://dx.doi.org/10.1038/cddis.2016.307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059890/
https://www.ncbi.nlm.nih.gov/pubmed/27685623
http://dx.doi.org/10.1038/cddis.2016.307

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