Combined application of anti-VEGF and anti-EGFR attenuates the growth and angiogenesis of colorectal cancer mainly through suppressing AKT and ERK signaling in mice model

BACKGROUND: Angiogenesis is generally involved during the cancer development and hematogenous metastasis. Vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR) are considered to have an important role in tumor-associated angiogenesis. However, the effects of simultane...

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Detalles Bibliográficos
Autores principales: Ding, Chenbo, Li, Longmei, Yang, Taoyu, Fan, Xiaobo, Wu, Guoqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059930/
https://www.ncbi.nlm.nih.gov/pubmed/27729020
http://dx.doi.org/10.1186/s12885-016-2834-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059930/
https://www.ncbi.nlm.nih.gov/pubmed/27729020
http://dx.doi.org/10.1186/s12885-016-2834-8

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