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Brief Report: Intraarticular Sprifermin Not Only Increases Cartilage Thickness, but Also Reduces Cartilage Loss: Location‐Independent Post Hoc Analysis Using Magnetic Resonance Imaging

OBJECTIVE: To determine whether an anabolic drug (sprifermin) is capable of reducing cartilage loss wherever it occurs in a given knee, using a subject‐specific, location‐independent analysis of cartilage change in patients with knee osteoarthritis (OA). METHODS: Study participants (n = 168; ages ≥4...

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Detalles Bibliográficos
Autores principales: Eckstein, Felix, Wirth, Wolfgang, Guermazi, Ali, Maschek, Susanne, Aydemir, Aida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061102/
https://www.ncbi.nlm.nih.gov/pubmed/26138203
http://dx.doi.org/10.1002/art.39265