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Oligoarginine Peptides Slow Strand Annealing and Assist Nonenzymatic RNA Replication

The nonenzymatic replication of RNA is thought to have been a critical process required for the origin of life. One unsolved difficulty with nonenzymatic RNA replication is that template-directed copying of RNA results in a double-stranded product; following strand separation, rapid strand reanneali...

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Detalles Bibliográficos
Autores principales: Jia, Tony Z., Fahrenbach, Albert C., Kamat, Neha P., Adamala, Katarzyna P., Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061144/
https://www.ncbi.nlm.nih.gov/pubmed/27657866
http://dx.doi.org/10.1038/nchem.2551