A High-Content Larval Zebrafish Brain Imaging Method for Small Molecule Drug Discovery

Drug discovery in whole-organisms such as zebrafish is a promising approach for identifying biologically-relevant lead compounds. However, high content imaging of zebrafish at cellular resolution is challenging due to the difficulty in orienting larvae en masse such that the cell type of interest is...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Harrison, Chen, Steven, Huang, Kevin, Kim, Jeffrey, Mo, Han, Iovine, Raffael, Gendre, Julie, Pascal, Pauline, Li, Qiang, Sun, Yaping, Dong, Zhiqiang, Arkin, Michelle, Guo, Su, Huang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061318/
https://www.ncbi.nlm.nih.gov/pubmed/27732643
http://dx.doi.org/10.1371/journal.pone.0164645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061318/
https://www.ncbi.nlm.nih.gov/pubmed/27732643
http://dx.doi.org/10.1371/journal.pone.0164645

Ejemplares similares