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A High-Content Larval Zebrafish Brain Imaging Method for Small Molecule Drug Discovery
Drug discovery in whole-organisms such as zebrafish is a promising approach for identifying biologically-relevant lead compounds. However, high content imaging of zebrafish at cellular resolution is challenging due to the difficulty in orienting larvae en masse such that the cell type of interest is...
Autores principales: | Liu, Harrison, Chen, Steven, Huang, Kevin, Kim, Jeffrey, Mo, Han, Iovine, Raffael, Gendre, Julie, Pascal, Pauline, Li, Qiang, Sun, Yaping, Dong, Zhiqiang, Arkin, Michelle, Guo, Su, Huang, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061318/ https://www.ncbi.nlm.nih.gov/pubmed/27732643 http://dx.doi.org/10.1371/journal.pone.0164645 |
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