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NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts

Natural Killer (NK) cell education, which requires the engagement of inhibitory NK cell receptors (iNKRs) by their ligands, is important for generating self-tolerant functional NK cells. While the potency of NK cell education is directly related to their functional potential upon stimulation with HL...

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Detalles Bibliográficos
Autores principales: Isitman, Gamze, Tremblay-McLean, Alexandra, Lisovsky, Irene, Bruneau, Julie, Lebouché, Bertrand, Routy, Jean-Pierre, Bernard, Nicole F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061331/
https://www.ncbi.nlm.nih.gov/pubmed/27732638
http://dx.doi.org/10.1371/journal.pone.0164517