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NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts
Natural Killer (NK) cell education, which requires the engagement of inhibitory NK cell receptors (iNKRs) by their ligands, is important for generating self-tolerant functional NK cells. While the potency of NK cell education is directly related to their functional potential upon stimulation with HL...
Autores principales: | Isitman, Gamze, Tremblay-McLean, Alexandra, Lisovsky, Irene, Bruneau, Julie, Lebouché, Bertrand, Routy, Jean-Pierre, Bernard, Nicole F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061331/ https://www.ncbi.nlm.nih.gov/pubmed/27732638 http://dx.doi.org/10.1371/journal.pone.0164517 |
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