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Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by ‘Entotheonella’

Sponge metagenomes are a useful platform to mine cryptic biosynthetic gene clusters responsible for production of natural products involved in the sponge-microbe association. Since numerous sponge-derived bioactive metabolites are biosynthesized by the symbiotic bacteria, this strategy may concurren...

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Detalles Bibliográficos
Autores principales: Nakashima, Yu, Egami, Yoko, Kimura, Miki, Wakimoto, Toshiyuki, Abe, Ikuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061366/
https://www.ncbi.nlm.nih.gov/pubmed/27732651
http://dx.doi.org/10.1371/journal.pone.0164468