A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses

Humans express seven human APOBEC3 proteins, which can inhibit viruses and endogenous retroelements through cytidine deaminase activity. The seven paralogs differ in the potency of their antiviral effects, as well as in their antiviral targets. One APOBEC3, APOBEC3C, is exceptional as it has been fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Wittkopp, Cristina J., Adolph, Madison B., Wu, Lily I., Chelico, Linda, Emerman, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061367/
https://www.ncbi.nlm.nih.gov/pubmed/27732658
http://dx.doi.org/10.1371/journal.ppat.1005865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061367/
https://www.ncbi.nlm.nih.gov/pubmed/27732658
http://dx.doi.org/10.1371/journal.ppat.1005865

Ejemplares similares