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A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses
Humans express seven human APOBEC3 proteins, which can inhibit viruses and endogenous retroelements through cytidine deaminase activity. The seven paralogs differ in the potency of their antiviral effects, as well as in their antiviral targets. One APOBEC3, APOBEC3C, is exceptional as it has been fo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061367/ https://www.ncbi.nlm.nih.gov/pubmed/27732658 http://dx.doi.org/10.1371/journal.ppat.1005865 |