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Digitized Spiral Drawing: A Possible Biomarker for Early Parkinson’s Disease
INTRODUCTION: Pre-clinical markers of Parkinson’s Disease (PD) are needed, and to be relevant in pre-clinical disease, they should be quantifiably abnormal in early disease as well. Handwriting is impaired early in PD and can be evaluated using computerized analysis of drawn spirals, capturing kinem...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061372/ https://www.ncbi.nlm.nih.gov/pubmed/27732597 http://dx.doi.org/10.1371/journal.pone.0162799 |