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Type I Interferons Induce T Regulatory 1 Responses and Restrict Humoral Immunity during Experimental Malaria

CD4 T cell-dependent antibody responses are essential for limiting Plasmodium parasite replication and the severity of malaria; however, the factors that regulate humoral immunity during highly inflammatory, Th1-biased systemic infections are poorly understood. Using genetic and biochemical approach...

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Detalles Bibliográficos
Autores principales: Zander, Ryan A., Guthmiller, Jenna J., Graham, Amy C., Pope, Rosemary L., Burke, Bradly E., Carr, Daniel J.J., Butler, Noah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061386/
https://www.ncbi.nlm.nih.gov/pubmed/27732671
http://dx.doi.org/10.1371/journal.ppat.1005945