Cargando…

Bacterial Expression, Purification and In Vitro Phosphorylation of Full-Length Ribosomal S6 Kinase 2 (RSK2)

Ribosomal S6 kinases (RSK) play important roles in cell signaling through the mitogen-activated protein kinase (MAPK) pathway. Each of the four RSK isoforms (RSK1-4) is a single polypeptide chain containing two kinase domains connected by a linker sequence with regulatory phosphorylation sites. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Utepbergenov, Darkhan, Hennig, Paulina M., Derewenda, Urszula, Artamonov, Mykhaylo V., Somlyo, Avril V., Derewenda, Zygmunt S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061434/
https://www.ncbi.nlm.nih.gov/pubmed/27732676
http://dx.doi.org/10.1371/journal.pone.0164343