High-throughput fingerprinting of human pluripotent stem cell factor responsiveness and lineage induction bias

Populations of cells create local environments that lead to emergent heterogeneity. This is particularly evident in human pluripotent stem cells (hPSCs) where microenvironmental heterogeneity limits cell fate control. We have developed a high-throughput platform to screen hPSCs in configurable micro...

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Detalles Bibliográficos
Autores principales: Nazareth, Emanuel J.P., Ostblom, Joel E.E., Lücker, Petra B., Shukla, Shreya, Alvarez, Manuel M., Oh, Steve K.W., Yin, Ting, Zandstra, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061564/
https://www.ncbi.nlm.nih.gov/pubmed/24141495
http://dx.doi.org/10.1038/nmeth.2684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061564/
https://www.ncbi.nlm.nih.gov/pubmed/24141495
http://dx.doi.org/10.1038/nmeth.2684

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